levocetirizine

Azelastine: dose, uses, side effects and properties

Azelastine is a newer H1 blocker, has good topical activity and additionally suppresses histamine release and inflammatory reactions caused by LTs (by inhibiting lipoxygenase) and PAF. It has been demonstrated to reduce intracellular adhesion molecule-1 (ICAM-1) expression on nasal mucosa after intranasal administration. It has a t½ of 24 hours, however due to the active […]

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Levocetirizine: dose, uses, side effects and properties

Levocetirizine is an H1 antihistamine that is used to treat a variety of allergic conditions. It is the active R-enantiomer of cetirizine. Levocetirizine do not cross blood-brain barrier. As compared to cetirizine, it is effective at half the dose and appears to cause less sedation and lack of anticholinergic side effects. Cetirizine and levocetirizine have

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Cetirizine: dose, uses, side effects and properties

Cetirizine is an H1 antihistamine that is used to treat a variety of allergic conditions. It is a metabolite of hydroxyzine with high affinity for peripheral H1 receptors. Cetirizine in addition inhibits release of histamine and of cytotoxic mediators from platelets as well as eosinophil chemotaxis during the secondary phase of the allergic response. Thus,

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