limitations and progress of hybridoma technique

Hybridoma technique is the most favored and efficient method for exploring and producing  monoclonal antibodies (mAbs). At present, The majority of the mAbs approved by the US-FDA are manufactured utilizing hybridoma technique. It is introduced by Kohler and Milstein in 1975 and got the Nobel prize in 1984. OKT3 (muromonantibody) against CD-3 is the first […]