Immunotoxins: structure, mechanism, uses and limitations
Immunotoxins are a new class of large molecules and targeted anticancer drugs. It is a conjugated protein containing an antibody, growth factor, or cytokine that binds directly to target cells and toxins (e.g. Diphtheria toxin) joined together with a pH-sensitive cross linker that serves as a disulfide bond in between. Like “magic bullets,” it destroys […]
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