CYP enzymes

pharmacokinetics

Pharmacokinetics

Introduction Pharmacokinetic is the kinesis (movement) of pharmacological substances (drugs) throughout the body, which includes all phases and processes from entering to leaving the body. It is merely “what the body does with the drug.” Those drug kinetics can be broadly divided into 4 (ADME): If the drug is administered intravenously, there are only three […]

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Daridorexant: dose, uses and side effects

Daridorexant (nemorexant) is a newer class of sedative-hypnotic drugs under non-benzodiazepine category. it is used to treat insomnia in adults. daridorexant blocks binding of wake promoting neuropeptides (orexin A and orexin B) to its receptors OX-1 and OX-2. It should be avoided in patients with depression. Drug class Orexin receptor antagonist, hypnotics Available preparation Daridorexant

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prodrugs list

Prodrugs: list, types, objectives and methods of prodrug designing

Prodrugs are described as inactive drugs that must be changed into one or more active metabolites within the body in order to exert the desired pharmacological effect. The prodrug may be more stable, have greater bioavailability, or other desired pharmacokinetic features, or have fewer side effects and toxicity than the active form. Some prodrugs are

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