Deflazacort is a synthetic glucocorticoid, with anti-inflammatory and immunomodulating properties. It is a prodrug, converts to active metabolite by plasma esterases. It has approved by the FDA to manage Duchenne Muscular Dystrophy (DMD). With less adverse effects on bone health and weight than other steroids, it improves the lives of children with DMD by delaying […]
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Pheniramine (most famous brand name ‘Avil’) is an H1 antihistamine, used to treat acute allergic conditions such as insect bite/sting, drug allergy, blood transfusion reaction etc. it is moderately sedative and produces other CNS side effects, as crosses blood-brain barrier. Drug class H1 antihistamine, 1st generation Available preparations pheniramine maleate Tablet: 25 mg, 50 mg
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Topical steroids are used to treat a wide range of dermatological illnesses. Their anti-inflammatory, immunosuppressive, vasoconstrictor, and antiproliferative (for scaling lesions) properties are major mechanism to use them topically. The extent of absorption to deeper layers determines the strength of action, and hence the lipophilicity of the molecule determines potency to a large extent. Fluorinated
Steroids or Corticosteroids are hormones produced by the adrenal cortex and are necessary for various physiological functions in the body. The terms ‘corticosteroid’ and ‘corticoid‘ are used interchangeably to refer to natural gluco- and mineralo-corticoids, and their synthetic analogues. Hydrocortisone is the major endogenous glucocorticoid, whereas aldosterone is the major endogenous mineralocorticoid. The key role of
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